Aug. 2018

A Method for Cryogenic Preservation of Human Biopsy Specimens and Subsequent Organoid Culture


​​​​Sep. 2015

RNA-Seq of single prostate CTCs implicates noncanonical Wnt signaling in antiandrogen resistance.


Sep. 2015

BET inhibitor resistance emerges from leukaemia stem cells.

 

Sep. 2015

Transcriptional plasticity promotes primary and acquired resistance to BET inhibition.


​Mar. 2015

Dual Function of Wnt Signaling during Neuronal Differentiation of Mouse Embryonic Stem Cells


Mar. 2015

Modeling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids.


Feb. 2015

Discovery of Potent, Orally Bioavailable, Small-Molecule Inhibitors of WNT Signaling from a Cell-Based Pathway Screen


​Feb. 2015
WNT signaling drives cholangiocarcinoma growth and can be pharmacologically inhibited.


Feb. 2015
Ascl2 Acts as an R-spondin/Wnt-Responsive Switch to Control Stemness in Intestinal Crypts.


Jan., 2015
Dkk1 haploinsufficiency requires expression of Bmp2 for bone anabolic activity.


Jan., 2015
The Endothelial Transcription Factor ERG Promotes Vascular Stability and Growth through Wnt/β-Catenin Signaling


Jan., 2015

Increased glutamine catabolism mediates bone anabolism in response to WNT signaling.


July 2014
A novel signaling pathway regulates colon cancer angiogenesis through Norrin


Nov., 2014
Harvard Researchers unveiled a novel Wnt signaling pathway controlling cancer metastases.


Oct., 2014
CRISPR-mediated direct mutation of cancer genes in the mouse liver


Dec., 2013
Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients​

Links

Copyright 2015. Time Bioscience. All Rights Reserved.

Partnership

Let's understand the Wnt signaling pathways

We appreciate the  great efforts from our partners





WORCESTER POLYTECHNIC INSTITUTE 

WPI LIFE SCIENCE AND ENGINEERING CENTER

WPI BIOPROCESS CENTER


​​Rudnicki Lab

Regenerative Medicine Program

Ottawa Hospital Research Institute

​University of Ottawa


Xi He Lab

​​Department of Neurology

Harvard Medical School