Division of Oral Biology and Medicine
the UCLA School of Dentistry
Dr. Wang is the leading investigator in the field of oral cancer, chronic inflammation, and adult stem cells. He has made a landmark discovery on the regulation of cancer cell death by NF-κB, a transcription factor associated with inflammation and immune responses.
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Let's understand the Wnt signaling pathways
Transcriptional plasticity promotes primary and acquired resistance to BET inhibition.
Modeling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids.
Discovery of Potent, Orally Bioavailable, Small-Molecule Inhibitors of WNT Signaling from a Cell-Based Pathway Screen
WNT signaling drives cholangiocarcinoma growth and can be pharmacologically inhibited.
Ascl2 Acts as an R-spondin/Wnt-Responsive Switch to Control Stemness in Intestinal Crypts.
Dkk1 haploinsufficiency requires expression of Bmp2 for bone anabolic activity.
The Endothelial Transcription Factor ERG Promotes Vascular Stability and Growth through Wnt/β-Catenin Signaling
Increased glutamine catabolism mediates bone anabolism in response to WNT signaling.
A novel signaling pathway regulates colon cancer angiogenesis through Norrin
Harvard Researchers unveiled a novel Wnt signaling pathway controlling cancer metastases.
CRISPR-mediated direct mutation of cancer genes in the mouse liver
Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients