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We proudly announce that we provide Wnt protein stabilizer. the stabilizer helps to maintain Wnt activity for more than 30 hours in serum-free culture conditions.
Our Wnt ligands are intact, potent, and fully functional.
Potent: The Wnt3a has been proved three times more potent than any one else; 30 to 100 ng/mL for organoid formation;
Intact: These Wnt ligands are purified using a Wnt ligands-binding molecule-conjugated sepharose beads and size exclusion chromatography. The affinity chromatography yields a single pool with strong Wnt activity rather than two pools;
Fully functional: The size exclusion chromatography removes dimers and cleaved Wnt proteins. Compared to two Wnt peaks from affinity chromatography, the Wnt3a is fully functional.
We express and purify human Wnt3a from a special human cell line. Our human Wnt3a has been proved as potent as the mouse one.
Leslie S. Gewin Lab at Vanderbilt - Journal of the American Society of Nephrology 28; 20017
Lawrence Lum's Lab at UT Southwestern Medical Center-PNAS Early Edition, J. Moon
The organizations who have proved our Wnt proteins
The working concentrations of Wnt3a are
Recombinant Wnt Signaling Ligands
Wnt protein stabilizer
Mouse Wnt Protein Control
Wnt Signaling Receptors